Experimental investigation of the possibility for proto-cell emergence

1) Reaction of proto-cell

* Gene replication by proto-cell

* Growth of lipid bilayer vesicle

2) Gene replication before enzyme generation

* Primitive replication of RNA

3) Genetic code protecting proto-cell


To make the studies on the origin of life more solid and concrete, it is essential to experimentally establish proto-cell models that allow researchers to test scenarios on how primordial cellular life originated.

In the studies of the pro to-cell through a constructive approach using biomolecules and computational analysis of genome information, ELSI researchers use a combination of synthetic and evolutionary biology to construct the proto-cell.

ELSI researchers are in the midst of experimentally developing simple cell models with metabolic reactions, gene replication, gene expression, and evolution.



Cellular multiplication cycle