Experimental investigation of the possibility for proto-cell emergence
1) Reaction of proto-cell
* Gene replication by proto-cell
* Growth of lipid bilayer vesicle
2) Gene replication before enzyme generation
* Primitive replication of RNA
3) Genetic code protecting proto-cell
To make the studies on the origin of life more solid and concrete, it is essential to experimentally establish proto-cell models that allow researchers to test scenarios on how primordial cellular life originated.
In the studies of the pro to-cell through a constructive approach using biomolecules and computational analysis of genome information, ELSI researchers use a combination of synthetic and evolutionary biology to construct the proto-cell.
ELSI researchers are in the midst of experimentally developing simple cell models with metabolic reactions, gene replication, gene expression, and evolution.
Cellular multiplication cycle