{"id":1101,"date":"2022-06-01T14:18:05","date_gmt":"2022-06-01T14:18:05","guid":{"rendered":"http:\/\/www.elsi.jp\/research\/research_fields_and_topics_old\/proto_cell_system\/"},"modified":"2022-06-02T09:18:05","modified_gmt":"2022-06-02T09:18:05","slug":"proto_cell_system","status":"publish","type":"page","link":"https:\/\/www.elsi.jp\/en\/research\/research_fields_and_topics_old\/proto_cell_system\/","title":{"rendered":"Research Topic 7. Proto-cell System"},"content":{"rendered":"\r\n<p><span>Goals<\/span><\/p>\n<p><span>Experimental investigation of the possibility for proto-cell emergence<\/span><\/p>\n<p><span>1) Reaction of proto-cell<\/span><\/p>\n<p><span>* Gene replication by proto-cell<\/span><\/p>\n<p><span>* Growth of lipid bilayer vesicle<\/span><\/p>\n<p><span>2) Gene replication before enzyme generation<\/span><\/p>\n<p><span>* Primitive replication of RNA<\/span><\/p>\n<p><span>3) Genetic code protecting proto-cell<\/span><\/p>\n<p><span>&nbsp;<\/span><\/p>\n<p><span>To make the studies on the origin of life more solid and concrete, it is essential to experimentally establish proto-cell models that allow researchers to test scenarios on how primordial cellular life originated.<\/span><\/p>\n<p><span>In the studies of the pro to-cell through a constructive approach using biomolecules and computational analysis of genome information, ELSI researchers use a combination of synthetic and evolutionary biology to construct the proto-cell.<\/span><\/p>\n<p><span>ELSI researchers are in the midst of experimentally developing simple cell models with metabolic reactions, gene replication, gene expression, and evolution.<\/span><\/p>\n<p><span>&nbsp;<\/span><\/p>\n<p style=\"text-align: center;\">\n<img decoding=\"async\" alt=\"topic7_E\" src=\"\/-\/media\/Project\/Elsi-Tenants\/Elsi-Tenant\/Elsi\/site\/topic7_E.jpg?h=316&amp;w=400&amp;la=en&amp;hash=EE1CBD5536535B9886EFCC6FC7742617B259DDA8\" style=\"height: 316px; width: 400px;\" \/><\/p>\n<p style=\"text-align: center;\"><span>Cellular multiplication cycle<\/span><\/p>        ","protected":false},"excerpt":{"rendered":"Goals Experimental investigation of the possibility for proto-cell emergence 1) Reaction of proto-cell * Gene replication by proto-cell * Growth of lipid bilayer vesicle 2) Gene replication before enzyme generation * Primitive replication of RNA 3) Genetic code protecting proto-cell &nbsp; To make the studies on the origin of life more solid and concrete, it [&hellip;]","protected":false},"author":9,"featured_media":0,"parent":1083,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_locale":"en_US","_original_post":"http:\/\/www.elsi.jp\/?page_id=1100"},"acf":[],"_links":{"self":[{"href":"https:\/\/www.elsi.jp\/wp-json\/wp\/v2\/pages\/1101"}],"collection":[{"href":"https:\/\/www.elsi.jp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.elsi.jp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.elsi.jp\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/www.elsi.jp\/wp-json\/wp\/v2\/comments?post=1101"}],"version-history":[{"count":1,"href":"https:\/\/www.elsi.jp\/wp-json\/wp\/v2\/pages\/1101\/revisions"}],"predecessor-version":[{"id":1102,"href":"https:\/\/www.elsi.jp\/wp-json\/wp\/v2\/pages\/1101\/revisions\/1102"}],"up":[{"embeddable":true,"href":"https:\/\/www.elsi.jp\/wp-json\/wp\/v2\/pages\/1083"}],"wp:attachment":[{"href":"https:\/\/www.elsi.jp\/wp-json\/wp\/v2\/media?parent=1101"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}