ELSI

研究・活動

研究者

Tony Z. Jia

Tony Z. Jia
氏 名
Tony Z. Jia
役 職
研究員
専門分野
生物化学
E-mail
tzjia_at_elsi.jp

主要業績/受賞歴

5. Enver C. Izgu, K. Anders Björkbom, Neha P. Kamat, Victor Lelyveld, Weicheng Zhang, Tony Z. Jia, Jack W. Szostak. N-Carboxyanhydride-Mediated Fatty Acylation of Amino Acids and Peptides for Functionalization of Protocell Membranes. J. Am. Chem. Soc., 138(51), 16669-16676 (2016)

4. Tony Z. Jia, Albert C. Fahrenbach, Neha P. Kamat, Katarzyna P. Adamala, Jack W. Szostak. Oligoarginine peptides slow strand annealing and assist non-enzymatic RNA replication. Nature Chem., 8, 915-921 (2016).

3. Tony Z. Jia, Christian Hentrich, Jack W. Szostak. Rapid RNA exchange in droplet based aqueous two-phase and coacervate systems. Orig. Life Evol. Biosph., 44(1), 1-12 (2014).

2. Katsuyuki Shiroguchi, Tony Z. Jia, Peter A. Sims, X. Sunney Xie. Digital RNA Sequencing Minimizes Sequence-Dependent Bias and Noise with Optimized Single Molecule Barcodes. Proc. Natl. Acad. Sci. USA, 109, 1347-1352 (2012).

1. Peera Jaru-Ampornpan, Kuang Shen, Vinh Q. Lam, Mona Ali, Sebastian Doniach, Tony Z. Jia, Shu-ou Shan. ATP-independent reversal of membrane protein aggregation by a novel chaperone. Nature Struct. Mol. Biol., 17, 696-702 (2010).

Patents:

X. Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia. Single Cell Nucleic Acid Detection and Analysis. US Patent 9,260,753. Filed March 22, 2012. Issued February 16, 2016.

研究概要

-Prebiotic RNA Replication
-Early RNA-peptide Coevolution
-Self-Assembly and Supramolecular Structures on the Early Earth
-Coacervates and Condensed-Phase Systems as Membrane-free Protocell Models
-Ancient Hydrogels

Education:

Harvard University 2016, Ph.D. in Chemistry
Harvard University 2012, A.M. in Chemistry
California Institute of Technology 2010, B.S. in Chemistry and Business, Economics, and Management